Prevalence of Mucosal Hyperplasia in the Appendix and Analysis of Its Histological Features and Causative Factors

Mucosal hyperplasia of the appendix was first described by MacGillivray. Hyperplastic lesions of the appendix appears either as hyperplasia and hyperplastic polyps. In the present study the incidence and causative factors for mucosal hyperplasia in the appendix. A total of 372 appendicectomy specimens were studied by normal H& E staining. A typical appearance of mucosal hyperplasia was observed in 27 cases out of 372 cases of appendicectomy. The mean age of the patients was 48.7 years and the ratio between male and female was 1: 1.2. Out of 27 cases, almost all the cases lumen was obstructed and the presence of lymphocytes and eosinophills in the lamina propria of the appendix was observed. This indicates the chronic inflammation with allergic reaction leading to mucosal hyperplasia of the appendix, since the hyperplasia is a benign process.